Seguin is one of the oldest towns in Texas.  In 1838 a group of Texas Rangers organized a settlement among live oaks above springs that fed the Guadalupe River.  The town was named for Juan Seguin, a Tejano patriot.

Seguin is large enough to boast a top-rated university, Texas Lutheran University, and the well-respected Guadalupe Regional Medical Center.  It is a diversified community offering a wide range of cultural, recreational, and employment opportunities.  In 2009, Seguin was proud to be selected by Caterpillar as the site of a major new engine manufacturing facility.